Preventing Skin Infections During Cancer Treatment

November 11, 2025

How to Protect Compromised Skin and Support Healing

Cancer treatments like chemotherapy and radiation can weaken your skin’s natural barrier, leaving it more vulnerable to irritation and infection. When the skin becomes dry, cracked, or broken, bacteria can enter more easily—leading to discomfort and delayed healing.


Understanding how to care for your skin properly during treatment can help prevent infections and support your overall well-being.


Why Skin Infections Are Common During Treatment


Radiation and chemotherapy target rapidly dividing cells, which includes not only cancer cells but also healthy skin cells. This slows your skin’s ability to repair itself. As a result, small irritations or wounds can take longer to heal, and the immune system may not be as strong in fighting off bacteria.


Keep the Skin Clean—But Gentle


Cleanliness is essential, but it’s important to avoid over-cleansing. Use a mild, fragrance-free cleanser and lukewarm water. Avoid scrubbing or using harsh washcloths. Gently pat the skin dry with a soft towel to prevent further irritation.


Moisturize to Maintain the Skin Barrier


Dry and cracked skin is more prone to infection. Apply a soothing, oncology-safe moisturizer several times a day, especially after cleansing. Look for gentle formulas that contain ceramides, glycerin, or aloe vera. Moisturizing regularly helps reinforce the skin’s natural defenses.


Watch for Early Signs of Infection


Even minor irritation can quickly turn into an infection if not treated.


Contact your healthcare provider if you notice:

  • Redness that spreads or worsens
  • Swelling or warmth in the affected area
  • Pus, fluid, or scabbing that doesn’t heal
  • Increased pain or fever


Prompt attention can prevent small issues from becoming more serious.


Avoid Irritants and Friction


Wearing soft, breathable fabrics can help reduce irritation. Avoid tight clothing or materials that trap heat and moisture. Stay away from perfumed lotions or harsh chemicals that can disrupt the skin barrier.


Kureology M.D.: Gentle Care for Vulnerable Skin


Kureology M.D. specializes in skincare products for sensitive and compromised skin, including those undergoing cancer treatments. Our dermatologist-developed formulas help maintain hydration, reduce irritation, and support healing—providing an extra layer of protection against infection.

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